INVESTIGADORES
ISLA Maria Ines
congresos y reuniones científicas
Título:
Bioactivities of Acacia species (A.atramentaria, A. aroma, and A. caven) of Argentina.
Autor/es:
ARIAS M., ZAMPINI I.C., VATTUONE M., ISLA M.I.
Lugar:
Tucumán
Reunión:
Congreso; Bio Cell 29(1) 108 (2005)- XXI Jornadas Científicas de la Asociación de Biología de Tucumán; 2004
Institución organizadora:
Asociación de Biología de Tucumán
Resumen:
The genus Acacia, one of the important genera of the family Fabaceae (Sub family Mimosaceae) includes aproximately 1350 species and is abundant in Australia, Africa, India and America. The aim of the present work is to compare the antibacterial and antioxidant activity of alcoholics extracts of three species of the Subgenus Acacia, A. aroma, A. atramentaria and A. caven. The antimicrobial activity was tested against bacteria of clinical relevance as nosocomial pathogens (Hospital of Clinicas Nicolas Avellaneda) by diffusion in agar, broth microdilution and agar macrodilution methods (NCCLS, 2002). The antioxidant activity was evaluated with stable free radical (DPPH) and the ß carotene-linoleate system. La toxicity was analyzed by Artemia salina test (LD50). Acacia aroma exhibited the strongest inhibitory effect on growth of Gram negative and positive bacteria with CIM values of 125 to 250 µg/ml. All extracts showed antioxidant activity. The more active was  A. atramentaria extract (0,38µg/ml). No toxicity was found (LD50 > 1000 ppm). Our results indicate the presence of compounds possessing high antioxidant and antibacterial activity in Argentine Acacia species. The marked activity of the extracts is partially attributed to its higher content of polyphenolic-compounds.