INVESTIGADORES
ISLA Maria Ines
artículos
Título:
Antiinflammatory activity of structuraly related natural flavonoids.
Autor/es:
ALBERTO MARÍA R., NIEVA MORENO MARÍA I., ZAMPINI IRIS C., ISLA MARÍA I.
Revista:
BOLETíN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMáTICAS
Editorial:
SOC FITOQUIMICA LATINOAMERICANA
Referencias:
Lugar: ---; Año: 2007 vol. 6 p. 308 - 309
ISSN:
0717-7917
Resumen:
ABSTRACT The present study was conduced to investigate the effect of two types of bioactive flavonoids, structurally related, isolated from Z. punctata on cyclooxigenase-2 (COX-2) and cyclooxygenase-1 (COX-1). Chalcone was more active than flavone on COX-2.   The cytoprotective and antioxidant activity demonstrated for both structurally related flavonoids may contribute to the anti-inflammatory effect.