INVESTIGADORES
ISLA Maria Ines
artículos
Título:
BIOACTIVITIES OF CHUQUIRAGA STRAMINEA
Autor/es:
MARIA ELENA MENDIONDO, BERTA E. JUAREZ, CATIANA ZAMPINI, MARIA INES ISLA, ROXANA ORDOÑEZ
Revista:
NATURAL PRODUCT COMMUNICATIONS
Editorial:
NATURAL PRODUCTS INC
Referencias:
Año: 2011 vol. 6 p. 965 - 968
ISSN:
1934-578X
Resumen:
Methanolic extracts of Chuquiraga straminea Sandwith, subfamily Barnadesioideae (Asteraceae) showed the presence of quercetin-3-O-glucoside, quercetin-3-O-rutinoside, kaempferol, kaempferol-3-O-glucoside and kaempferol-3-O-rutinoside. Antioxidant and antimicrobial activity was determined. The total extracts showed antioxidant activity by DPPH and ABTS method (SC50 14.5 to 34.9 µg/mL). A significantly positive correlation was observed between the antioxidant activity and the total phenolics (R>0.93). The  extracts were active against ten methicillin resistant and sensitive S. aureus strains isolated from nosocomial infection (MIC values between 200 to 800 ìg/mL). These preliminary studies are highly interesting as they open new ways for further applications in the treatment of infections by methicillin resistant Staphylococcus aureus