ISLA Maria Ines
Antioxidant and anti-inflammatory activity characterization and genotoxicity evaluation of Ziziphus mistol ripe berries, exotic Argentinean fruit
CARDOZO MARIA LUZ, ORDOÑEZ ROXANA MABEL,ALBERTO MARIA, ZAMPINI IRIS, ISLA MARIA INES
FOOD RESEARCH INTERNATIONAL
ELSEVIER SCIENCE BV
Año: 2011 vol. 44 p. 2063 - 2071
Ziziphus mistol Griseb. (Rhamnaceae), popularly known as ¡°mistol,¡± is widely distributed throughout Peru, Bolivia, Paraguay and Argentina. Its fruit is consumed in different forms in several Argentinean communities.The aim of this work is to quantify Z. mistol fruit macronutrients and phytochemicals as well as to determine its functional antioxidant and anti-inflammatory properties and toxicity after two different processes: boiling and hydroalcoholic extraction. Phytochemical recovery was variable depending on the extraction method used. All preparations showed antioxidant activity, but the ethanolic one (EME) was significantly more active than the aqueous one (AME) as hydrogen or electron donors with SC50 values between 1.45 to 6.31 ugGAE/ mL and 7.38 to 64.77 ug GAE/mL, respectively. The aqueous extraction was significantly more active than EME equivalents (GAE)/mL but the decoction did not. On the other hand, extracts did not show any mutagenic effect. Therefore, mistol fruits consumption could be encouraged not only for its functional properties, but also because of the positive ecological impact of preserving biological diversity through the exploitation of native natural resources in a regional economy.