INVESTIGADORES
IGLESIAS Alberto Alvaro
libros
Título:
An Introduction to Metabolic and Cellular Engineering, Second Edition
Autor/es:
S. CORTASSA; M.A. AON; A.A. IGLESIAS; J.C. AON; D. LLOYD
Editorial:
World Scientific Publishers
Referencias:
Lugar: Singapur; Año: 2012 p. 428
ISSN:
978-981-4365-71-0
Resumen:
AN INTRODUCTION TO METABOLIC AND CELLULAR ENGINEERING
Second Edition
by S Cortassa (Johns Hopkins University, USA), M A Aon (Johns Hopkins University, USA), A A Iglesias (Universidad del Litoral, Argentina), J C Aon (GlaxoSmithKline, USA),
&
D Lloyd (Cardiff University, UK)
Table of Contents (46k)Preface (35k)Chapter 1: Introduction (3,294k)
Metabolic and Cellular Engineering (MCE) is more than an
exciting scientific enterprise. It has become the cornerstone for coping
with the challenges ahead of mankind. Continuous developments, new
concepts, and technological innovations will enable us to deal with
emerging challenges, and solve problems once thought impossible ten
years ago. Challenges in MCE are broad- from unraveling fundamental
aspects of cellular function to meeting unsatiated energy and food
demands that are rising in parallel with population growth.
In charting the progress of MCE during the last decade, we could
not help but feel in awe of the enormous strides of progress made from
the nascent Metabolic Engineering to the Systems Bioengineering of
today. The burgeoning availability of genomic sequences from diverse
species has been spectacular. It has become the engine that drives the
genetic means for the modification of existing organisms and the
generation of synthetic, man-made ones. From the initial attempts at
purposeful genetic modification of a cell for the production of valuable
compounds, we have now moved on to changing microbes genetically or
metabolically.
The arsenal of experimental and theoretical tools available for
Metabolic and Cellular Engineering has expanded enormously, driven by
the re-emergence of Physiology as Systems Biology. The revival of the
concept of networks fueled by new developments has become central to
Systems Biology. Networks represent an integrative vision of how
processes of disparate nature relate to each other, and as such is
becoming a key analytical and conceptual tool for MCE. This book
reflects and addresses all these ongoing changes while providing the
essential conceptual and analytical tools needed to understand and work
in the MCE research field.
Contents:
Introduction
Matter and Energy Balances
Cell Growth and Metabolite Production: Basic Concepts
Engineering of Process Performance
Modeling Networks: Concepts and Tools
Dynamic Aspects of Bioprocess Behavior
Bioprocess Development with Plant Cells
Animal Cell Culture Techniques
Metabolic and Cellular Engineering and Bioprocess Engineering in the Industrial Production of Therapeutic Proteins
Systems Biology of Metabolic and Cellular Engineering
Readership: Students,
undergraduates, graduates and professionals contributing to or are in
the field of Metabolic and Cellular Engineering.