INVESTIGADORES
GORLA Nora Bibiana Maria
artículos
Título:
Spontaneous chromosome aberrations in Fanconi?s anemia patients are located at fragüe sites and acute myeloid leukemia breakpoints
Autor/es:
FUNDIA A F; GORLA N; LARRIPA I
Revista:
HEREDITAS
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 1994
ISSN:
0018-0661
Resumen:
Spontaneous chromosome aberrations (CA) were analyzed in 3 Fanconi?s anemia (FA) patients, 8 family members, and 9 healthy individuáis. Peripheral blood lymphocytes obtained from each individual were cultured and cytogenetic analysis was performed on standard and sequential G-banded metaphases. The numbers of abnormal cells and breaks were found to be higher in AF patients compared to the other groups (p