INVESTIGADORES
GORLA Nora Bibiana Maria
artículos
Título:
STUDIES ON THE MECHANISM OF GLUTATHION PREVENTION OF CARBON TETRACHLORIDE-INDUCED LIVER INJURY.
Autor/es:
GORLA N B, FERREYRA E C DE, VILLARRUEL M C, FENOS O M DE, CASTRO J A
Revista:
BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 1983 p. 388 - 395
ISSN:
0007-1021
Resumen:
The prior administration of GSH partially prevents CCl4 induced liver necrosis observed at 24h after administration of the hepatotoxin. Results are interpreted as suggesting that GSH prevents CCl4 induced liver necrosis by modification of early events of the process such as lipid peroxidation or covalent binding of reactive metabolites.