INVESTIGADORES
GEFFNER Jorge Raul
artículos
Título:
The role of semen in sexual transmission of HIV: beyond a carrier for virus particles.
Autor/es:
SABATTÉ J, LENICOV FR, CABRINI M, RODRIGUEZ CR, OSTROWSKI M, CEBALLOS A, AMIGORENA S, GEFFNER J.
Revista:
MICROBES AND INFECTION
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2011 vol. 13 p. 977 - 982
ISSN:
1286-4579
Resumen:
Unprotected sexual intercourse between discordant couples is by far the most frequent mode of HIV-1 (human immunodeficiency virus type 1) transmission being semen the main vector for HIV-1 dissemination worldwide. Semen is usually considered merely as a vehicle for HIV-1 transmission. In this review we discuss recent observations suggesting that beyond being a carrier for virus particles semen markedly influences the early events involved in sexual transmission of HIV through the mucosal barriers.