INQUISUR   21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Hydration studies on lipid membranes: Classification of water molecules near the bilayer in gel and liquid phase.
Autor/es:
LAUREANO ALARCON; MARIA B. SIERRA; MARCELA A. MORINI; VIVIANA I. PEDRONI; GUSTAVO A. APPIGNANESI; ANIBAL DISALVO
Lugar:
Santiago del Estero
Reunión:
Congreso; XLIV Reunión Anual de la Sociedad Argentina de Biofísica; 2015
Resumen:
We studied the hydration of membranes composed of dipalmitoylphosphatidylcholine (DPPC) lipid molecules, revealing that the water molecules do not only moisturize the polar groups of the lipids, but also penetrate through alkane chains of such molecules. To characterize these lipid systems and compare them with other systems as hydrophobic and hydrophilic monolayers we study different parameters, such as density fluctuation, residence times and orientation of the water molecules on the surface of the monolayer, in addition to typical parameters in lipid membranes as area per lipid and number of water molecules per lipid. Furthermore, we discriminate water molecules surrounding the lipid membrane, ranking them according to their distances (and residence times) on different atoms composing the lipid bilayer. These studies were conducted both in liquid phase and gel phase.