Endothelial effects of magnetic nanocarriers composed by magnetite, oleic acid and chitosan intended to drug delivery devices

MARIELA A. AGOTEGARAY; ADRIAN CAMPELO; VIRGINIA L. MASSHEIMER; VERÓNICA L. LASSALLE

Córdoba

Congreso; Reunión Internacional de Ciencias Farmacéuticas (RICIFA); 2014

Magnetic nanoparticles (MNPs) are promising systems intended for target and delivery of several drugs due to their ability to orient the therapeutic agent to a desired part of the body by the application an external magnetic field. Two magnetic nanodevices were evaluated in endothelial cells (ECs) cultures to study cell viability. Formulations consist in a magnetic core composed by magnetite functionalized with oleic acid and recovered with crosslinked (N1) and non-crosslinked chitosan (N2).