Catalyst-free, efficient and selective synthesis of asymetric diarylsulfones

LO FIEGO, M.J.; BADAJOZ, M; CHOPA, A.B.; LOCKHART, M.T.

Basilea

Congreso; 16th International Electronic Conference in Synthetic Organic Chemistry (16 ECSOC),; 2012

The synthetic potential of the catalyst-free reaction of arylstannanes and sulfonyl chlorides, for the generation of asymmetric diarylsulfones, is described. Moreover, the efficiency of the reaction is improved using diarylstannanes as starting substrates. All the reactions studied went, exclusively, through an ipso-substitution and give acceptable yields of sulfones from aryl sulfonyl chlorides supporting either electron-releasing or electron-attracting substituents. A special work up is carried out in order to recover the di- and trialkyltin chlorides generated as subproducts.