Magnetic Nanocarriers For The Controlled Release Of Diclofenac

AGOTEGARAY MARIELA; PALMA, SANTIAGO DANIEL; LASALLE, VERONICA

Rosario

Congreso; 2da Reunion Internacional de Ciencias Farmaceuticas; 2012

Magnetic nanoparticles(MNPs) find active applications in biomedical field, for example, as targeted drug delivery systems. Their development is suitable for transporting a specific drug directly to the site of disease avoiding adverse effects over different parts of the body(1). We have developed a novel device consisting in iron oxide [magnetite(MG), Fe3O4]  MNPs coated with oleic acid(OA) and chitosan(CS) for the delivery of the anti-inflammatory drug Diclofenac. A study of the in vitro release of the drug has been performed.