INQUISUR   21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Synthesis of optically active derivatives of bicyclic chiral diols with C2 symmetry
Autor/es:
F. C. M. ZACCONI; L. C. KOLL; J. C. PODESTÁ
Lugar:
Congreso Electrónico http://www.usc.es/congresos/ecsoc/14/
Reunión:
Congreso; ECSOC 14 (14th Electronic Conference on Synthetic Organic Chemistry); 2010
Institución organizadora:
MDPI
Resumen:
Efficient synthesis, besides other, of dibromide, diazide, diamine and diesters derived from (11R,12R)-9,10-dihydroanthracene-11,12-dimethanol (3), a chiral bicyclic diol with C2 symmetry, was developed. Esterification with 3 of saturated and unsaturated carboxylic acids and acids chlorides leads to the corresponding normal-, olefinic- and acetylenic diesters in average yields of 81%. Also more efficient techniques for the preparation of starting diol 3 in higher yields as well as for a very simple separtion of DCU from reactions carried out following DCC/DMAP method are described