INQUISUR   21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
artículos
Título:
Synthesis of organotin derivatives of optically active eleven-membered macrodiolides
Autor/es:
GERBINO, DARÍO CÉSAR; GERBINO, DARÍO CÉSAR; SCOCCIA, JIMENA; SCOCCIA, JIMENA; PODESTÁ, JULIO CÉSAR; PODESTÁ, JULIO CÉSAR
Revista:
TETRAHEDRON-ASYMMETRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2016 vol. 27 p. 352 - 360
ISSN:
0957-4166
Resumen:
The synthesis and the results obtained in the hydrostannation of eight new TADDOL diacrylates andmethacrylates are reported. The addition of triorganotin hydrides, R3SnH, 12?14 (R = nBu, neophyl, Ph,respectively) to diesters 6?11 containing different combinations of substituents at the C-2 carbon ofthe dioxolane ring, led to macrocyclization products in all cases. The cyclohydrostannation of diacrylate10 proceeded with complete diastereoselectivity. The cyclohydrostannation of diesters 33 and 34 withhydrides 12 and 14 in all cases only afforded one stannylated macrocycle.