INQUISUR   21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
artículos
Título:
Synthesis of Polydopamine-Like Nanocapsules via Removal of a Sacrificial Mesoporous Silica Template with Water
Autor/es:
BAEZA, ALEJANDRO; RUIZ-MOLINA, DANIEL; GUISASOLA, EDUARDO; VALLET-REGÍ, MARÍA; NADOR, FABIANA; MORENO VILLAECIJA, MIGUEL ANGEL
Revista:
CHEMISTRY-A EUROPEAN JOURNAL
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Lugar: Weinheim; Año: 2016 vol. 23 p. 2753 - 2758
ISSN:
0947-6539
Resumen:
Hollow polymeric polydopamine (PDA) micro-/nanocapsules have been obtained through a very simple, mild, and straightforward method that involves coating of silica mesoporous nanoparticles through an ammonia-triggered polymerization of PDA and the posterior removal of the sacrificial template simply by dispersion in water, without the need of any harsh chemical reagent, either in the presence or absence of active principles, from doxorubicinto iron oxide nanoparticles. To demonstrate the potential of the nanocapsules obtained with this new approach, they have been successfully used as nanocarriers for drug delivery.