INQUISUR 21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
artículos
Título:
The synthesis of C2 symmetry diesters of (3R,4R)-TTFOL through a green and stereoselective (2R,3R)-TADDOL rearrangement
Autor/es:
ANDREA ROSANA COSTANTINO; MARÍA GABRIELA MONTIEL SCHNEIDER; ANTONIO GALMÁDEZ; ROMINA ANDREA OCAMPO; SANDRA DELIA MANDOLESI; LILIANA CRISTINA KOLL
Revista:
TETRAHEDRON-ASYMMETRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2015 vol. 26 p. 1341 - 1347
ISSN:
0957-4166
Resumen:
An efficient, green, and atom economic methodology for the stereoselective synthesis of C2 symmetry (3R,4R)-TTFOL diester derivatives has been developed. The procedure occurs through a (2R,3R)-TADDOL dioxolane cleavage and rearrangement under mild conditions by its reaction with a carboxylic acid in the presence of TFAA/H3PO4without the need for an inert atmosphere to give generally highyields.
