congresos y reuniones científicas
Ex vivo HIV-1 infection of non-suppressive FOXP3+Treg cells induces a unique pattern of cytokine secretion
FAINBOIM, L ; ARRUVITO, L; GEFFNER, J; SABATTE, J
Congreso; 6th IAS Conference on HIV Pathogenesis, Treatment and Prevention; 2011
6th IAS Conference on HIV Pathogenesis, Treatment and Prevention
The role of Treg cells in HIV-1 infected individuals has been controversial; because it was either suggested that may suppress HIV-specific T cell response or protect individuals from immune activation. All these studies were performed without taking into account the phenotypic and functional heterogeneity of FOXP3+ Tregs. Thus, the present study assessed in HIV individuals the absolute number of Treg with suppressor capacity and those which secreted cytokines.