CYTc is a mitochondrial regulator of arabidopsis development

MANSILLA N; GONZALEZ DH; RACCA S; WELCHEN E; CANAL V; GRAS D

Congreso; LASDB Meeting 2019 Xth Meeting of the Latin American Society for Developmental Biology; 2019

From embryogenesis and seed germination to senescence and death, plant development is theresult of successive delineated stages connecting transcriptional networks, metabolism anddifferent hormonal pathways that must be fine-tuned with plant-environment interactions.CYTc is a small hemeprotein faced to the inner mitochondrial membrane, that transferselectrons to Complex IV during the last step of aerobic cellular respiration for ATP production.Lack of CYTc generates the arrest of embryo development at early stages duringembryogenesis. Plants with CYTc deficiency have less biomass, delayed growth anddevelopment, with alterations in the carbohydrate metabolism and the active Gibberellins andDELLAs homeostasis. Modified CYTc levels impacts on the length of hypocotyls and roots andalso in the root cell composition, in a hormonal-dependent manner. By using different loss and gain-of-function mutants, we explored the possible connection between CYTc-dependentmitochondrial respiration to the pathways controlled by the TOR and SnRK1 central metabolickinases and observed their responses and impacts on growth and development in thebackground of plants with modified CYTc levels.