INVESTIGADORES
CENTRON Daniela
artículos
Título:
blaOXA-51 type ß-lactamase genes are ubiquitous and vary within a strain in Acinetobacter baumannii.
Autor/es:
MERKIER AK; CENTRÓN, D
Revista:
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Editorial:
Elsevier
Referencias:
Lugar: Londres; Año: 2006 vol. 28 p. 110 - 113
ISSN:
0924-8579
Resumen:
We investigated the spread of bla(OXA-51)-type beta-lactamase genes in 200 Acinetobacter spp. clinical strains isolated in Argentina from 1982 to 2005. bla(OXA-51)-type genes were present in all Acinetobacter baumannii isolates tested (n=194), whereas they were not detected in two Acinetobacter haemolyticus, two genomic species 10 or two Acinetobacter lwoffii isolates. The bla(OXA-51)-type alleles varied within a strain and were found in six different A. baumannii pulsed-field gel electrophoresis clones that were susceptible or resistant to imipenem, suggesting a controversial role in imipenem resistance. Our findings agree with previous reports showing that bla(OXA-51)-type genes are naturally harboured by A. baumannii isolates from various geographical origins and support the presence of a direct reservoir of beta-lactam resistance genes within the nosocomial environment.
