INVESTIGADORES
CAMPERI Silvia Andrea
capítulos de libros
Título:
Solid-Phase Peptide Synthesis Using ChemMatrix®, a Polyethylenglycol (PEG)-based Solid
Autor/es:
F. ALBERICIO; N. BAYO; S. A. CAMPERI; O. CASCONE; S. CÔTÉ; L. J. CRUZ; A. ERRACHID; R. FURIC; F. GARCÍA-MARTÍN; Y. GARCÍA-RAMOS; N. B. IANNUCCI; M. M. MARANI; M. PLA-ROCA; M. QUINTANAR-AUDELO; J. SAMITIER; J. TULLA-PUCHE
Libro:
Understanding Biology Using Peptides
Editorial:
Springer
Referencias:
Lugar: New York; Año: 2006; p. 114 - 115
Resumen:
Polystyrene (PS) and PEG-PS resins are currently the most widely used supports for SPS. Although large numbers of peptides and small molecules can be prepared using these supports, there is an ever-increasing need for resins that are suited to more universal applications. In this regard, amphiphilic matrices containing only PEG are very attractive. ChemMatrix® (Fig. 1), a novel 100% PEG-based resin,  is herein introduced. ChemMatrix® exhibits good loading and is a user friendly resin. It shows excellent performance for the preparation of hydrophobic peptides as well as for one-bead-one-peptide libraries. Nanotechnologic techniques like FIB (Focused Ion Beam) will be used for the bead-by-bead characterization of ChemMatrix®.® (Fig. 1), a novel 100% PEG-based resin,  is herein introduced. ChemMatrix® exhibits good loading and is a user friendly resin. It shows excellent performance for the preparation of hydrophobic peptides as well as for one-bead-one-peptide libraries. Nanotechnologic techniques like FIB (Focused Ion Beam) will be used for the bead-by-bead characterization of ChemMatrix®.