INVESTIGADORES
CABRERA Gabriela Myriam
artículos
Título:
Antioxidant Neolignans from Cordia americana
Autor/es:
LUCÍA R FERNANDEZ; ADRIANA M CIRIGLIANO; MARIA FABANI; BEATRIZ LIMA; SEBASTIÁN ALBERTI; FERNANDO KRAMER; ALEJANDRO TAPIA; GABRIELA M CABRERA; JORGE A. PALERMO; MARIANELA SANCHEZ
Revista:
PLANTA MEDICA
Editorial:
GEORG THIEME VERLAG KG
Referencias:
Año: 2013 p. 1724 - 1729
ISSN:
0032-0943
Resumen:
Five new neolignans with a bicyclo[2.2.2]octene framework were isolated from an ethanolic extract of the bark of Cordia americana. The structures and relative configurations of the compounds were elucidated by a combination of spectroscopic methods. All the isolated compounds showed good antioxidant activities in the DPPH radical scavenging and Ferric-reducing antioxidant power assays. One of the compounds displayed mild fungistatic activity at 0.1 µmol/spot against Fusarium virguliforme while, at the same time, all compounds were inactive against several strains of Gram (+) and Gram (-) bacteria at all assayed concentrations.