INVESTIGADORES
CABRERA Gabriela Myriam
artículos
Título:
Antimicrobial metabolites produced by an intertidal Acremonium furcatum
Autor/es:
GABRIELA L. GALLARDO; MATÍAS BUTLER; MARIANA L. GALLO; M. ALEJANDRA RODRÍGUEZ; MARCOS N. EBERLIN; GABRIELA M. CABRERA
Revista:
PHYTOCHEMISTRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2006 vol. 67 p. 2403 - 2410
ISSN:
0031-9422
Resumen:
In a screening for antimicrobial metabolites, amides of D-allo- and L-isoleucine derivatives were isolated from the culture of a marine strain of Acremonium furcatum. Structural elucidation of these compounds was performed by analysis of spectroscopic data and confirmed by synthesis. All of the compounds, natural and synthetic intermediates, were bioassayed against bacteria and phytopathogenic fungi, with many showing remarkable antifungal activities.