Discrimination between surgical and non-surgical nuclear cataracts based on ROC analysis

PAZ FILGUEIRA CLEMENTE; SÁNCHEZ ROBERTO; COLOMBO ELISA; MERITXELL VILASECA; JAUME PUJOL; ISSOLIO LUIS

CURRENT EYE RESEARCH

TAYLOR & FRANCIS INC

Lugar: Londres; Año: 2014 p. 1 - 7

0271-3683

PURPOSE: The aim of this paper is to propose a quantitative methodology for determining a criterion to discriminate non-surgical nuclear cataract from surgical ones taking into account objective measures of intraocular scattering in patients with good visual acuity (>0.6). METHODS: Two groups of subjects were taken into account: a control group and a group with nuclear cataracts. At a first stage, eyes belonging to the cataract group were classified into non-surgical and surgical cataracts by ophthalmologists at their clinical settings. At a second stage a double pass instrument was also used to determine the Objective Scatter Index (OSI) at the laboratory. ROC curves were used to analyze OSI values to determine a value able to separate between non-surgical and surgical cataracts. RESULTS: We obtained statistically significant differences among the control and both nuclear cataract groups (p