INQUINOA   21218
INSTITUTO DE QUIMICA DEL NOROESTE
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Effect of Thymoquinone on DMPC liposomes: Study by FTIR, Raman and SERS spectroscopies.
Autor/es:
S. B. DIAZ; A. BEN ALTABEF; M. E. DEFONSI LESTARD; M. E. TUTTOLOMONDO
Lugar:
S. M. de Tucumán
Reunión:
Congreso; SAB2016; 2016
Institución organizadora:
SAB
Resumen:
Agreat deal of natural origin quinones has pharmacologically interestingproperties [1].Thymoquinone (TQ) is one of the most studied quinines because ofits potential anti-cancer, anti-oxidant and anti-inflammatory effects [2].However,the molecular pathways involved in  theseactivitiesare not well understood.Hence, we decided to carry out research on TQ interactionof with model lipid membranes.Inthis work,TQ interaction of with dipalmiristoylphosphatidylcholine(DMPC) bilayers was studied by FTIR, Raman and SERS spectroscopies.The resultsshowed that TQ interacted to different extents with the phosphate and carbonylgroups of membranes in the gel and the liquid crystalline states.