Fern Acylphloroglucinols: Structure, Location, and Biological Effects

CECILIA SOCOLSKY; MARCELA A. HERNÁNDEZ; ALICIA BARDÓN

Studies in Natural Products Chemistry

Elsevier

Lugar: Londres; Año: 2012; p. 105 - 157

Among fern acylphloroglucinols, a large number comes from European species of the genus Dryopteris, the one that deserved the most extensive phytochemical studies through the years. These derivatives have been incorporated to the present review together with acylphloroglucinols isolated from a few other genera. In addition, we presented in a tabular way, an important group of phloroglucinol derivatives that have been isolated from Argentine species of the genus Elaphoglossum. These compounds, isolated in our laboratories in the past 8 years, have been identified employing modern spectroscopic techniques, particularly 600 MHz NMR and High Resolution?Mass Spectrometry after exhaustive isolation and purification employing HPLC. Evaluation of their bioactivity revealed that their molluscicidal effects are the most significant and that they are comparable, in potency, to the synthetic molluscicides employed in the control of snails of the genus Biomphalaria, the known schistosomiasis vectors.