INQUINOA 21218
INSTITUTO DE QUIMICA DEL NOROESTE
Unidad Ejecutora - UE
artículos
Título:
Acyl thiourea derivatives: A study of crystallographic, bonding, biological and spectral properties
Autor/es:
PIRO, O.E.; TUTTOLOMONDO, M.E.; CONTRERAS AGUILAR, E.; ULIC, S.E.; MOLINA, R.D.I.; ECHEVERRÍA, G.A.; JIOS, J.L.; ARENA, M.E.
Revista:
CHEMICAL PHYSICS LETTERS
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2019 vol. 715 p. 64 - 71
ISSN:
0009-2614
Resumen:
The study of two new acylthiourea derivatives (Ar-CO-NH-CS-NH-R) are focused on the bonding interactions supported by X-ray, NMR, UV?Vis, Raman and IR spectroscopy, and NBO, AIM and Hirshfeld surface analysis.The RAHB model is proposed to explain some structural properties. The molecules are stabilized by intra-molecular NH⋯O bonds arranged in the lattice as centre symmetric dimers held by inter-molecular NH⋯S bonds.The dimers are linked to each other through NH⋯O bonds giving rise to a chain, ribbon-like structure in the network. In vitro bacterial growth inhibition, biofilm formation, biosensor and biofilm metabolic activity were tested considering the broad bioactivity of acylthioureas.
