INQUINOA 21218
INSTITUTO DE QUIMICA DEL NOROESTE
Unidad Ejecutora - UE
artículos
Título:
Phloroglucinols from the Argentine ferns Elaphoglossum gayanun and E. piloselloides
Autor/es:
CECILIA SOCOLSKY; SUSANA A. BORKOSKY; MARCELA HERNÁNDEZ DE TERÁN; YOSHINORI ASAKAWA; ALICIA BARDÓN
Revista:
JOURNAL OF NATURAL PRODUCTS
Editorial:
AMER CHEMICAL SOC
Referencias:
Año: 2010 vol. 73 p. 901 - 904
ISSN:
0163-3864
Resumen:
Five new prenylated phloroglucinols were isolated from the diethyl ether extracts of the ferns Elaphoglossum gayanum and E. piloselloides. Their structures were established by analysis of their spectroscopic data (1D and 2D NMR, HRMS, and IR) and chemical derivatization. The two major compounds exhibited moderate molluscicidal activity against the snail Biomphalaria peregrina, a vector of the tropical disease schistosomiasis, with LD50 7.2 μg/mL (14.4 μM) and 11.7 μg/mL (22.2 μM).
