INSTITUTO DE BIOTECNOLOGIA Y BIOLOGIA MOLECULAR
Unidad Ejecutora - UE
congresos y reuniones científicas
The psorosis disease of citrus: a pale light at the end of the tunnel.
PEDRO MORENO; JOSE GUERRI; MARIA LAURA GARCIA
Otro; REVIEW, IOCV; 2015
Abstract First reported in 1896, psorosis was the first citrus disease proven to be grafttransmissible and also the first for which eradication and budwood certification programs werelaunched to prevent its economic damage. For many years psorosis etiology remained elusiveand only in 1986 it was associated with the presence of virus-like particles in infected plants.However, in the last two decades a virus with unusual morphology (Citrus psorosis virus, CPsV)was characterized and closely associated with psorosis disease as previously defined by fieldsymptoms and by biological indexing in sensitive indicator plants. With a tripartite, negativesense, RNA genome and a ~48 kDa coat protein, CPsV, the presumed causal agent of psorosis,is the type member of the genus Ophiovirus, within the new family Ophioviridae. Availability ofthe complete genomic sequence of two CPsV isolates and partial sequences of many othershas enabled i) setting up rapid and sensitive RNA-based detection methods, ii) testing differentcitrus and relatives for resistance to CPsV, iii) identification of the two components (psorosis Aand psorosis B) traditionally associated with non-scaled and scaled bark inoculum, respectively,from psorosis-infected plants and study their interactions, iv) analysis of genetic variation andevolutionary forces shaping the CPsV populations, v) preliminary studies on the interactionsbetween virus and host factors and vi) development of transgenic citrus plants expressing variabledegrees of resistance to CPsV. In summary, 120 years after the first report on psorosis we startseeing a pale light at the end of the tunnel.