Molecular population genetic analysis of emerged bacterial pathogens

GAILLARD, MARIA EMILIA; BOTTERO, DANIELA; FERNANDEZ, JULIETA; SISTI, FEDERICO; CASTUMA, C; HOZBOR, DANIELA

Bacterial Populations: Basic and Applied Aspects of Their Structure and Evolution

RESEARCH SIGNPOST TRANSWORLD RESEARCH NETWORK

Año: 2010; p. 61 - 78

  Investigations on population genetics of bacterial pathogens have contributed to analyze episodes of temporal variation in disease severity and frequency. These analyses point out the fact that distinct bacterial clones are responsible for disease outbreaks and increases in infection frequency. Many of these clones are characterized by unique combinations of virulence genesor alleles of virulence genes. This review will summarize the insights accrued from population genetic analysis of different bacteria, which are responsible for relevant public heath infectious diseases.