IGEVET   21075
INSTITUTO DE GENETICA VETERINARIA "ING. FERNANDO NOEL DULOUT"
Unidad Ejecutora - UE
capítulos de libros
Título:
Genotoxic effects of Malnutrition and Infections in Argentinean children
Autor/es:
PADULA G.; SEOANE A.I.
Libro:
Malnutrition: Risk Factors, Health Effects and Prevention
Editorial:
Nova Science Publishers, Inc.
Referencias:
Lugar: Hauppauge, New York; Año: 2011; p. 91 - 100
Resumen:
The purpose of this study was to evaluate the relationship between malnutrition, bacterial infections and citogenetic damage. In order to obtain the frequencies of structural chromosomal aberrations (SCAs) in peripheral blood lymphocytes, we sample malnourished and eutrophic children with and without bacterial infections. Fifty infants concurrent to the Hospital Interzonal de Agudos y Crónicos Dr. Alejandro Korn, La Plata, Argentina were included in this study; 14 malnourished and non-infected (MN), 11 malnourished and infected (MI), 18 eutrophic and non-infected (EN) and 7 eutrophic and infected (EI). Children aged 1-60 months. Anthropometric and clinic evaluation were performed to assess nutritional condition. Before blood collection, we interviewed each individual´s parent to complete a semistructural survey specifying age, dietary habits, bacterial diseases; previous exposure to diagnostic x-rays; and use of therapeutic drugs. After48hours, 100 cultured lymphocytes were analyzed per individual. Statistical analysis was performed by the Epi Info 6.0, through the Pearson χ2 Test (p