ANTICESTODAL AND ANTITREMATODAL DRUGS

C. LANUSSE, G. VIRKEL, L. ALVAREZ

Veterinary Pharmacology and Therapeutics

wiley-blackwell

Lugar: Iowa; Año: 2009; p. 1095 - 1118

Fasciolosis, caused by the cosmopolitan parasite Fasciola hepatica, is the most common and economically important trematode disease of domestic animals worldwide. Additionally, fasciolosis is an important zoonotic disease, particularly in underdeveloped countries (Mas-Coma 2004). Chemotherapy, based on the use of flukicidal compounds, is the main tool to control liver flukes. Most of the antitrematodal drugs discussed herein are compounds used for the treatment of fasciolosis. The tropical counterpart of Fasciola hepatica is Fasciola gigantica and all drugs against one of the species are equally effective against the other (Boray 1986). Furthermore on this section, treatment of infections caused by rumen flukes (Paramphistomum spp.) in cattle and sheep and by lung flukes (Paragonimus spp.) in dogs and cats are briefly discussed.