Abstract:Non invasive hormone monitoring in chinchilla: ranking the steroid excretion in rodents.

BUSSO J.M.; PONZIO M.F; FIOL DE CUNEO M; RUIZ R.D,

BIOCELL

INST HISTOL EMBRIOL-CONICET

Año: 2011 vol. 35 p. 253 - 253

0327-9545

Whether the steroid hormone is primarily passed into urine or feces is species-dependent, and this information is useful to a precise endocrine monitoring; in excretes metabolite concentrations arefrequently several times higher than the concentration in blood.Wild Chinchilla lanigera is threatened (CITES I), although, domesticated form is widespread in breeding farms. Our experience on its reproductive endocrinology rises from radioinfusion studiesof testosterone (in males), estradiol, progesterone (in females) and corticosterone (in both sexes). Testosterone, estradiol and corticosterone metabolites were excreted mainly by urine (84.7±4.2%, 71.7±12.1%, 86.9±0.07% respectively), while progesterone was detected in equal amounts of both excretes. Therefore, we proposed that the urinary route is preferential in Hystricognathi (chinchilla and guinea pigs; currently considered cavy-like forms) while inthe Sciurognathi (squirrel and mouse-like forms, formerly considered Sciumorpha or Myormorpha suborders). This hypothesis was tested by matching our results and those reported for other rodents subjected to radiolabeled infusions. We consider that this proposal is relevant when the endocrine studies are faced in a new species.Supported by grants from SECyT-UNC, CONICET, FONCyT.