INTEQUI   20941
INSTITUTO DE INVESTIGACIONES EN TECNOLOGIA QUIMICA
Unidad Ejecutora - UE
artículos
Título:
Synthesis, physicochemical and biological studies of a ternary Co(II) complex with sulfaquinoxaline and 2,20-bipyrimidine as ligands
Autor/es:
J. F. CADAVID-VARGAS; M. E. CHACÓN VILLALBA; G. C. VALENCIA-URIBE; C. VILLA-PÉREZ; F. GIANNINI; I. C. ORTEGA; D. B. SORIA; GERARDO E. CAMÍ; G: ECHEVERRÍA; S. B. ETCHEVERRY
Revista:
INORGANICA CHIMICA ACTA
Editorial:
ELSEVIER SCIENCE SA
Referencias:
Lugar: Amsterdam; Año: 2016 vol. 447 p. 127 - 133
ISSN:
0020-1693
Resumen:
A novel ternary complex of Cobalt(II) with 4-amino-N-2-quinoxalinylbenzenesulfonamide (sulfaquinoxaline,SQO), and 2,20-bipyrimidine (Bpym) as ligands has been prepared. The complex has been characterizedbased on elemental analyses, FTIR and Raman spectroscopy. Its structure, [Co(SQO)2(Bpym)] wasdetermined by X-ray diffraction methods. It crystallizes in the triclinic P1 space group with a = 10.5381(2), b = 13.6469(2), c = 13.8409(3) Å, a = 95.058(2), b = 93.769(2), c = 93.750(2) and Z = 2 moleculesper unit cell. Thermogravimetric (TG) and differential thermal analysis (DT) were also studied.The aquatic toxicity of the complex was evaluated on the two following test organisms: Danio rerio(cebritas) y Cyprinus carpio haematopterus (carpas koi). Antibacterial activity was screened againstEscherichia coli (ATCC 8739), Salmonella typhimurium (ATCC 14028), Staphylococcus aureus (ATCC 49775)and Bacillus cereus (ATCC 10987). The antiproliferative effect of the tested complex [Co(SQO)2(Bpym)] inthe human osteoblast (MG-63) cell line was also studied.