INTEQUI 20941
INSTITUTO DE INVESTIGACIONES EN TECNOLOGIA QUIMICA
Unidad Ejecutora - UE
artículos
Título:
Insect Growth Regulatory Effects of Linear Diterpenoids and Derivatives from Baccharis thymifolia
Autor/es:
JUAN HIKAWCZUK, V.E.; SAAD, J.R.; GIORDANO, O.S.; GARCÍA, C.; MARTÍN, T.; MARTÍN, V.S.; SOSA, M.E.; TONN, C.E.
Revista:
JOURNAL OF NATURAL PRODUCTS
Editorial:
American Chemical Society
Referencias:
Lugar: New York; Año: 2008 vol. 71 p. 190 - 194
ISSN:
0163-3864
Resumen:
Abstract. Linear diterpenes isolated from aerial parts of Baccharis thymifolia Hook & Arn. (1-3) were tested for insect growth inhibitory activities against Tenebrio molitor L. larvae. Compounds 4-16 were prepared by several chemical transformations including double bonds asymmetric oxidations at the polyene chain. The most interesting results were attributed to the diterpenes 6,10-(E,E)-thymifodioic acid (1), 6,10-(E,E)-thymifodioic acid butenolide (3) and to the derivatives 4, 11, and 14. These compounds produced several development deficiencies in assays of topication on the fifth instar larvae. Compound 3 is a new alicyclic diterpene.
