INTEQUI 20941
INSTITUTO DE INVESTIGACIONES EN TECNOLOGIA QUIMICA
Unidad Ejecutora - UE
artículos
Título:
Expanding thetoolboxforenantioselectivesulfide oxidations: Streptomyces strainsasbiocatalysts
Autor/es:
MASCOTTI ML; PALAZZOLO M; LEWKOWICZ E; KURINA SANZ M
Revista:
Biocatalysis and Agricultural Biotechnology
Editorial:
Elsevier
Referencias:
Año: 2013 vol. 2 p. 399 - 402
ISSN:
1878-8181
Resumen:
Sulfide oxidase activity ofStreptomyces genus is reported here for the first time. Three Streptomyces strains were selected as new tools to access to enantioenriched R- and S-dialkyl sulfoxides. The bacterial screening was carried out using cyclohexyl methyl sulfide as model substrate.Both sulfoxide antipodes were obtained in a one-pot, time-dependent biotransformation employing S. phaeochromogenes NCIMB 11741 as biocatalyst. S. flavogriseus ATCC 33331produced mainly the S-enantiomer, while S. hiroshimensis ATCC 27429 yielded enantiopure R-cyclohexyl methyl sulfoxide.
