CONSUMED IN THE PROVINCE OF SAN JUAN, ARGENTINA

PUERTA M L; LIMA, B; VIDAL E; CABALLERO D; LUNA L; BAUDINO O; TAPIA, A; SUERO E

BIOCELL

INST HISTOL EMBRIOL-CONICET

Lugar: Mendoza; Año: 2014

0327-9545

Urinary Tract Infections (UTIs) affect men and women of all ages, usually resolve without any complications but in some cases persist. The recurrent UTIs are treated in the majority of cases with antimicrobial profilaxis, increasing the problem of antibiotic resistance. Generally, it is considered that Escherichia coli is the essential causative agent of 80% of the UTIs. In our country, UTIs in women are a frequent reason for medical consultation. Approximately 25 to 35% of women between 20 and 40 years have had an episode of UTIs during her life. The cranberry has been proposed as an effective agent in the prevention and treatment of UTIs. In vitro antibacterial activity of acidified methanolic extracts (EMeOH) from Mendoza, Tucuman and Entre Rios cranberry cultivars was determined using the microbroth dilution method according to the protocols of the Clinical and Laboratory Standards Institute CLSI protocols. The EMeOH showed antibacterial activity against Escherichia coli ATCC 25922 and Escherichia coli clinical isolates from Laboratorio de Microbiología, Hospital Marcial Quiroga (San Juan, Argentina) with MICs values of 2000 µg/ml and 3000 µg/ml respectively. Chemical studies of characterization and quantification of phenolic compounds, flavonoids and anthocyanins are in progress.