INQUISAL   20936
INSTITUTO DE QUIMICA DE SAN LUIS "DR. ROBERTO ANTONIO OLSINA"
Unidad Ejecutora - UE
artículos
Título:
Preconcentration and post-column fluorescent derivatization for the environmental water monitoring of an antihelmintic macrocyclic drug used in livestock
Autor/es:
WANG, CHIEN C.; PEREYRA, VÍCTOR; FELICI, EMILIANO; VICARIO, ANA; CASADO, CRISTIAN; GÓMEZ, MARÍA R.
Revista:
Heliyon
Editorial:
Elsevier Ltd
Referencias:
Lugar: Londres; Año: 2019 vol. 5 p. 1 - 7
ISSN:
2405-8440
Resumen:
In this paper, a green analytical methodology based on fluorescence derivatization is proposed for the anti-helminthic drug monitoring ivermectin as environmental emergent contaminant. After sample clean-up, ivermectin was converted into a highly fluorescent derivative through a catalytic oxidation process followed by dehydration and tautomerization. Under optimal experimental conditions, a linear response was obtained for ivermectin within the range 0.38?600 μg L−1, with detection and quantification limits of 0.11 and 0.38 μg L−1, both values are lower than other previously reported. This method has been applied for ivermectin determination in environmental water samples at trace levels, showing its potential for contamination monitoring.