JEREZ Susana Josefina
congresos y reuniones científicas
Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
JEREZ, SUSANA; MEDINA, ANALIA; ALARCÓN, GABRIELA; SIERRA, LILIANA; MEDINA, MIRTA
Conferencia; III Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-Link; 2021
Universidad Central de Chile. Facultad de Ingeniería y Arquitectura; Instituto de Agroquímica y Tecnología de Alimentos
Cold pressed chia seed oils (ChO) are known for health-promoting characteristics due to the high content of omega-3 α-linolenic acid (ω-3 ALA). We investigated the influence of ChO supplementation as functional food on animal models of cardiovascular risk factors: hypercholesterolemia and metabolic syndrome (MS). Dietary intervention with ChO (equivalent to 4.8 g ALA per day) was found to improve the vascular dysfunction and mitigate the rise in plasma triglyceride (TG) levels under hypercholesterolemic conditions. However, impaired glucose tolerance was found in control ChO treated animals. In order to verify whether the effects of chia seed are the same as that of ChO, we replaced the ChO for an equivalent amount of seed. Glucose intolerance was found once again. For this reason, we carried out a new study in which the ChO intake was reduced to 3 g ALA per day, and no alterations were observed in such conditions. Thus, dietary intervention with ChO equivalent to 3 g ALA intake per day was choose to analyze the effects on the alterations that characterize the high fat diet induced-MS. ChO supplementation lowered ω-6 / ω-3 ratio, TG, blood pressure and improved endothelial function. Nevertheless, ChO worsened the high fat diet deleterious effects on visceral abdominal fat, fasting glucose and glucose tolerance. Our results support the view that dietary guidelines for treating patients with hypercholesterolemia or MS must be carefully planned, in such a way that the incorporation of ChO into the diet should be controlled and nutritional background considered.