IHEM 20887
INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS
Unidad Ejecutora - UE
artículos
Título:
Dehydro-leucodin: a guaiane-type sesquiterpene lactone
Autor/es:
HORACIO A. PRIESTAP; KHALIL A. ABBOUD; ALVARO E. VELANDIA; LUIS A. LOPEZ; MANUEL A. BARBIERI
Revista:
ACTA CRYSTALLOGRAPHICA SECTION E
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Año: 2011 vol. 67 p. 3470 - 3470
ISSN:
1600-5368
Resumen:
Dehydroleucodin [systematic name: (1S,6S,2R)-9,13-dimethyl-5-methylene-3-oxatricyclo[8.3.0.02,6]trideca-9,12-diene-4,11-dione], C15H16O3, is a guanolide isolated from Artemisia douglasiana. The fused-ring system contains a seven-membered ring that adopts a chair conformation, a fused planar cyclopentenone ring and a five-membered lactone ring fused in envelope conformation. The absolute structure determined by X-ray analysis agrees with that previously assigned to this compound by NMR studies [Bohlmann & Zdero (1972 ). Tetrahedron Lett. 13, 621624] and also with that of leucodine, a closely related guaianolide [Martinez et al. (1988 ). J. Nat. Prod. 51, 221228].
