IMBECU   20882
INSTITUTO DE MEDICINA Y BIOLOGIA EXPERIMENTAL DE CUYO
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Effect of geometrically different environments as novelty attractors on the lateralized exploratory response in maturing rats
Autor/es:
LARIO R.; ALVAREZ EO; RATTI S.G.,
Lugar:
Buenos Aires
Reunión:
Congreso; LXII REUNIÓN ANUAL DE LA SOCIEDAD ARGENTINA DE INVESTIGACIÓN CLÍNICA (SAIC); 2017
Institución organizadora:
SAIC
Resumen:
It is known that the brain is functionally lateralized to control several biological responses in man and animals. However, its intrinsic neural mechanisms are not known. Previously in our laboratory, results were shown that in the Double Hole-Board Labyrinth (LDHB), maturing normal rats show a left-biased exploration induced by novelty. Since the LDHB is composed of two solid rectangular compartments disposed in 90º to each other (inverted ?T? form), question was raised if the rat?s brain lateralized behavioural response should be constant in any geometrically shaped environment. The answer to this question should enlighten the possible plasticity in the lateralized responses of the animal. Maturing normal rats at 30 days of age were used. They were tested in the LDHB (n=20) as a complex geometrical environment (SRT); in a rectangular cage (n=18), as a rectangular environment (SR), and a cubic cage (n=18), as a square environment (SQ). Exploration activity was video recorded and measured by digital automatic counter. Results are expressed as Counts/min. Results shown that in the SQ, right-biased exploration was found (74.5±9, left side Vs 118±12, right side, p