IMBECU   20882
INSTITUTO DE MEDICINA Y BIOLOGIA EXPERIMENTAL DE CUYO
Unidad Ejecutora - UE
artículos
Título:
Dietary (-)-epicatechin affects NF-κB activation and NADPH oxidases in the kidney cortex of high-fructose-fed rats
Autor/es:
PRINCE, PAULA DENISE; GALLEANO, MÓNICA; FRAGA, CÉSAR G.; RODRÍGUEZ LANZI, CECILIA
Revista:
Food and Function
Editorial:
Royal Society of Chemistry
Referencias:
Año: 2019 vol. 10 p. 26 - 32
ISSN:
2042-6496
Resumen:
Inflammation involves the activation of redox-sensitive transcription factors, e.g., nuclear factor κB (NF-κB). Administration of (-)-epicatechin to high-fructose-fed rats prevented NF-κB activation and up-regulation of the NADPH oxidase 4 (NOX4) in the kidney cortex. These results add mechanistic insights into the action of (-)-epicatechin diminishing inflammatory responses.