CONICET | Buscador de Institutos y Recursos Humanos

As a prevalent cardiovascular disease, heart failure is one of the leading causes of morbidity and premature mortality. Therefore, there is a special interest in the study of efficient markers associated with risk and / or prediction of cardiovascular events. Thus, they are proposed to multiple candidates, but especially those involved in oxidative and inflammatory processes typical of cardiovascular disease such as superoxide anion, nitric oxide and peroxynitrite. In this sense, there is a lack of knowledge about the potential utilities of these systems as biomarkers. This review aims to contribute to a better understanding of these systems for a better characterization of patients. On the other hand, a deep knowledge of these complex systems would also allow proposing new lines of research for the development of unpublished therapeutic tools as an auspicious frontier for the approach of this pathology.