IMBECU   20882
INSTITUTO DE MEDICINA Y BIOLOGIA EXPERIMENTAL DE CUYO
Unidad Ejecutora - UE
artículos
Título:
Hsp70/nitric oxide relationship in apoptotic modulation
Autor/es:
WALTER MANUCHA; PATRICIA G. VALLES
Revista:
CELL STRESS & CHAPERONES.
Editorial:
Cell Stress Society International
Referencias:
Año: 2008 vol. 13 p. 407 - 420
ISSN:
1355-8145
Resumen:
The functional integrity of the kidney depends on the normal development as well as on the physiological cell turnover, apoptosis induction being essential for these mechanisms. Multiple mechanisms are unleashed during the obstructive nephropathy, being programmed cell death that leads to renal tubular atrophy and tubular loss, one of the most complex. This review will focus on the nitric oxide and the Hsp70 interaction and regulation on the renal anti-apoptotic and the protective oxidative stress responses.