INVESTIGADORES
ALANIZ Laura Daniela
capítulos de libros
Título:
Determination of cell surface hyaluronan through flow cytometry
Autor/es:
VITALE DAINA; FIORELLA SPINELLI; ALANIZ LAURA
Libro:
The Extracellular Matrix: Methods and Protocols
Editorial:
SPRINGER
Referencias:
Año: 2019; p. 111 - 116
Resumen:
Hyaluronan is the major glycosaminoglycan present in the extracellular matrix of several cell types; its synthesis occurs on the cellular plasma membrane. Variations in its expression are related to alterations in cell proliferation, adhesion, and migration. It is able to interact with different binding proteins called hyaladherins, which can be conjugated to different fluorochromes and analyzed by flow cytometry.