INCITAP 20787
INSTITUTO DE CIENCIAS DE LA TIERRA Y AMBIENTALES DE LA PAMPA
Unidad Ejecutora - UE
artículos
Título:
Study of the Effects of Psidium cattleyanum on Gene Expression from Senescent Mouse Hippocampus
Autor/es:
RAMIREZ MR, APEL MA, ZANCHIN NILSON I,ZUANAZZI JAS, HENRIQUES AT
Revista:
BOLETÃN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMáTICAS
Editorial:
SOC FITOQUIMICA LATINOAMERICANA
Referencias:
Lugar: Santiago de Chile; Año: 2012 p. 127 - 137
ISSN:
0717 7917
Resumen:
In this work, we report a characterization of gene expression profiles of mice hippocampus by use microarray after treatment with Psidium cattleyanum fruit (1000 mg/kg oral). After eight months, no toxic effects were detected with the supplementation. Genes differentially expressed include genes involved in a wide range of physiological functions, such as metabolism, transport, signal transduction and a group of genes whose function has not yet been identified. These results suggest that global analysis of gene expression might be useful to elucidate the mechanisms of beneficial phytochemical action and may also help to identify potential targets for further investigation.
