INCITAP   20787
INSTITUTO DE CIENCIAS DE LA TIERRA Y AMBIENTALES DE LA PAMPA
Unidad Ejecutora - UE
artículos
Título:
Experimental infection of rabbits (Cuniculis orictolagus) with Brucella suis biovar 1 isolated from wild hares (Lepus europaeus)
Autor/es:
FORT, MARCELO; BALDONE, VALERIA; FUCHS, LUMILA; GIMENEZ, HUGO; ROJAS, MARÍA; BRECCIA, JAVIER; OYHENART, JORGE
Revista:
VETERINARY MICROBIOLOGY
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Año: 2011
ISSN:
0378-1135
Resumen:
Brucella suis biovar 1 is the causative agent of brucellosis in several domestic and wild animals and it is a common agent of human brucellosis. European hares (Lepus europaeus) have been shown to be infected by B. suis biovar 1 and the transmission to other animals has been suggested. In this work, experimental rabbits (Cuniculis orictolagus) were infected with Brucella suis biovar 1 isolated from wild hares. Infected rabbits showed high serological response in 2 weeks after discharge and typical granulomatous lesions (2 mm diameter) were found in liver, spleen and kidneys after 50 days. Brucella suis biovar 1 was cultured from the lesion of the organs mentioned above as well as from urine, placenta and fetuses. These data suggest that hares are a potential source for horizontal transmission of Brucella suis biovar 1 to other mammalians.