Bioavailability reduction of aflatoxin b1 and performance of broiler chickens fed with native Pichia kudriavzevii

MAGNOLI AP; ; RODRIGUEZ MC; ; PERALTA MF; ; NILSON A; ; MIAZZO RD;; DALCERO AM;; CHIACCHIERA SM; ; CAVAGLIERI L.

Congreso; VIII congreso brasileiro de micologia; 2016

Aflatoxin B1 (AFB1) is a mycotoxin produced by Aspergillus flavus and A. parasiticus and produces severeeconomic losses and health problems in poultry because of its toxicity and frequency of occurrence infeedstuffs. The toxicity of AFB1 in broilers includes carcinogenic, mutagenic, teratogenic, and growthinhibitory effects. One of the most practical solutions to this problem is the use of non-nutritive adsorbentsincorporated to the diets. These substances sequester the toxin in the gastrointestinal tract forming insolublecomplexes which are removed with faeces. Others additives such as yeast and yeast cell wall products have alsobeen suggested more recently for reducing aflatoxicosis in poultry. The aim of this study was to evaluate theefficacy of native yeast strains from broilers feedstuff, in reducing the toxicity of aflatoxin in broilers fed a dietnaturally contaminated. Cobb broilers (160) of 1-day-old were randomly assigned to 4 dietary treatments, T1:basal diet (B); T2: B + yeast 0.1%; T3: B + AFB1 (100 μg/kg); T4: B + yeast 0.1% + AFB1 (100 μg/kg).Productive parameters (body weight gain -BWG-, feed consumption -FC-, feed conversion ratio -FCR-, carcassyield -CY- and dead weight -DW), biochemical (ALB, GLOB and ALB/GLOB), liver pathological changes andAFB1 residual levels in livers were investigated. Significant differences (P