Proton-induced single electron capture on DNA/RNA bases

C. CHAMPION; P. F. WECK; H. LEKADIR; M. E. GALASSI; O. A. FOJÓN; P. ABUFAGER; R. D. RIVAROLA; J. HANSSEN

PHYSICS IN MEDICINE AND BIOLOGY

IOP PUBLISHING LTD

Lugar: Bristol; Año: 2012 vol. 57 p. 3039 - 3049

0031-9155

In this work, we report total cross sections for the single electron capture process induced on DNA/RNA bases by high-energy protons. The calculations are performed within both the continuum distorted wave and the continuum distorted wave-eikonal initial state approximations. The biological targets are described within the framework of self-consistent methods based on the complete neglect of differential overlap model whose accuracy has first been checked for simpler bio-molecules such as water vapour. Furthermore, the multi-electronic problem investigated here is reduced to a mono-electronic one using a version of the independent electron approximation. Finally, the obtained theoretical predictions are confronted with the scarcely available experimental results./RNA bases by high-energy protons. The calculations are performed within both the continuum distorted wave and the continuum distorted wave-eikonal initial state approximations. The biological targets are described within the framework of self-consistent methods based on the complete neglect of differential overlap model whose accuracy has first been checked for simpler bio-molecules such as water vapour. Furthermore, the multi-electronic problem investigated here is reduced to a mono-electronic one using a version of the independent electron approximation. Finally, the obtained theoretical predictions are confronted with the scarcely available experimental results.