IBCN   20355
INSTITUTO DE BIOLOGIA CELULAR Y NEUROCIENCIA "PROFESOR EDUARDO DE ROBERTIS"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Pattern Separation in humans in virtual reality environment
Autor/es:
RODRÍGUEZ, MARÍA; GARCÍA BAUZA. CRISTIAN; RAMÍREZ-BUTAVAND, DANIELA; LAZO, MARCOS G.; BALLARINI, FABRICIO; CIFUENTES, MARÍA V.; BEKINSCHTEIN, PEDRO
Lugar:
Mar del Plata
Reunión:
Congreso; XXXII Congreso Anual SAN 2017; 2017
Institución organizadora:
Sociedad Argentina de Investigación en Neurociencias
Resumen:
The ability to separate the components of memories into distinct complexmemory representations that are unique and less easily confused is thought to rely on amechanism called ??pattern separation?. The objective of this work is to study this mechanismin humans in a virtual reality environment, which allows to develop a task similar to the onewe use to study pattern separation in rodents.The task consists of collecting two flags that can be separated by different angles and duringa test session, indicate a flag that is located in the middle between the two previous ones. Inrodents, pattern separation has been shown to be modulated by factors such as exercise.Preliminary results from our study show that in sedentary people are not able to differentiatethe memories of the location of the flags when these are separated by a small angle (sincethey are too similar) whereas for a larger angle they succeed. This work could be important toassess the similarity between the mechanisms of pattern separation in rodents and humansand point at new ways of enhancing episodic memory in humans.