Effective connectivity in epileotigenic networks. Preliminary results.

KOCHEN SILVIA; COLLAVINI SANTIAGO; BLENKMANN ALEJANDRO

Buenos Aires

Congreso; Latin American Congress on Epilepsy 2014; 2014

International League Against Epilepsy

ObjectiveWe want to cuantitatively analyze the epileptogenic networks organization during seizures. This may have implications in the diagnosis and resective surgical treatment of epilepsy.MethodsTwo intracranial EEG (iEEG) seizures of one patient were studied. All channels from the epileptogenic network were selected based on iEEG interpretations.We defined nodes as the cortical region that represents the difference of adjacent chanels activity.Frequency bands betwen 0.5 ? 200 Hz were analized. Connectivity betwen nodes was measured using Partial Directed Coherence (PDC) as in [1]. Connectivities significatly higher than inter-ictal state in the sames nodes were considered (p